Treatment of High-Grade Pre-Neoplastic Cervical Lesions (CIN 2/3)

PHASE2CompletedINTERVENTIONAL
Enrollment

134

Participants

Timeline

Start Date

July 31, 2016

Primary Completion Date

May 24, 2022

Study Completion Date

November 22, 2022

Conditions
Cervical Intraepithelial NeoplasiaCervical Dysplasia
Interventions
DRUG

9-valent HPV vaccine

All women (regardless of age) will be administered a dose of the HPV vaccine on day of enrollment (regardless of previous HPV vaccination history). Women previously unvaccinated will receive an additional booster dose at 8 weeks.

DRUG

Imiquimod

At the baseline visit, this group will be instructed about the correct method of self-application of imiquimod 6.25mg as a vaginal suppository and receive a 16 week course of the drug.

Trial Locations (1)

06510

Smilow Cancer Hospital at Yale New Haven, New Haven

All Listed Sponsors
lead

Yale University

OTHER

NCT02864147 - Treatment of High-Grade Pre-Neoplastic Cervical Lesions (CIN 2/3) | Biotech Hunter | Biotech Hunter