Vision Restoration With a Collagen Crosslinked Boston Keratoprosthesis Unit

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

76

Participants

Timeline

Start Date

March 15, 2017

Primary Completion Date

June 30, 2021

Study Completion Date

August 31, 2021

Conditions
Keratolysis
Interventions
DRUG

Riboflavin

Riboflavin, a water soluble vitamin, is an essential nutrient and a natural component of many foods.

DRUG

Dextran

Dextran is used to increase the viscosity of the solution.

DEVICE

UVA Light Source

Avedro's KXL® System is a UVA irradiation system that uses a light emitting diode (LED) to deliver a dose of UVA light to a targeted treatment area for illuminating the cornea during corneal collagen cross-linking.

Trial Locations (13)

14642

David and Ilene Flaum Eye Institute, University of Rochester, New York

19007

Wills Eye, Bala-Cynwyd

21287

Wilmer Eye Institute, Baltimore

33136

Bascom Palmer eye Institute, Miami

41017

Cincinnati Eye Institute, Edgewood

44106

University Hospitals Eye Institute, Cleveland

48105

W.K. Kellogg Eye Center, Ann Arbor

60612

Illinois Eye and Ear Infirmary, Chicago

64111

Tauber Eye Center, Kansas City

78236

Wilford Hall Ambulatory Surgical Center (WHASC), Lackland Air Force Base

92093

Shiley Eye Institute, University of California, San Diego, San Diego

95817

UC Davis Health System Eye Center, Sacramento

90095-7003

The Jules Stein Eye Institute, Los Angeles

All Listed Sponsors
collaborator

United States Department of Defense

FED

lead

Joseph B. Ciolino, MD

OTHER

NCT02863809 - Vision Restoration With a Collagen Crosslinked Boston Keratoprosthesis Unit | Biotech Hunter | Biotech Hunter