Trial of Faecal Microbiota Transplantation in Cirrhosis

PHASE3CompletedINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

March 27, 2018

Primary Completion Date

September 30, 2019

Study Completion Date

September 30, 2019

Conditions
Cirrhosis of the Liver
Interventions
BIOLOGICAL

Faecal microbiota transplantation

The FMT (200mls) will be administered following preparation of the bowel with MoviPrep®, into the duodenum via a gastroscope derived from 50g of fresh donated stool from a healthy donor. The gastroscopy will be performed as per the King's College Hospital Gastroenterology Protocol.

BIOLOGICAL

Placebo

An identical appearing placebo solution (200mls 0.9% normal saline and 12.5% glycerol) will be administered into the duodenum via a gastroscope in a single blinded fashion following preparation of the bowel with MoviPrep®.

Trial Locations (1)

SE5 9RS

King's College Hospital NHS Foundation Trust, London

All Listed Sponsors
collaborator

King's College Hospital NHS Trust

OTHER

lead

King's College London

OTHER

NCT02862249 - Trial of Faecal Microbiota Transplantation in Cirrhosis | Biotech Hunter | Biotech Hunter