195
Participants
Start Date
January 24, 2017
Primary Completion Date
December 2, 2020
Study Completion Date
April 16, 2025
elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide or bictegravir/emtricitabine/tenofovir alafenamide or other medically-appropriate FDA-approved antiretroviral therapy
Participants received one tablet of elvitegravir 150mg/cobicistat 150mg/emtricitabine 200mg/tenofovir alafenamide 10mg by mouth daily with food or one tablet of bictegravir 50mg/emtricitabine 200mg/tenofovir alafenamide 25mg by mouth daily with or without food. Other non-study-provided ARV regimens were allowed for participants who were pregnant, breastfeeding, or unable/unwilling to take EVG/COBI/FTC/TAF or BIC/FTC/TAF, or for participants whose local health care/primary care provider preferred starting a different initial ARV regimen.
Barranco CRS, Lima
7804 Weill Cornell Chelsea CRS, New York
Columbia Physicians and Surgeons CRS (30329), New York
31802 Thai Red Cross AIDS Research Center Treatment (TRC-ARC Treatment) CRS, Bangkok
Pittsburgh CRS (1001), Pittsburgh
6201 Penn Therapeutics CRS, Philadelphia
Whitman Walker Health CRS (31791), Washington D.C.
Instituto de Pesquisa Clinica Evandro Chagas (12101), Rio de Janeiro
Greensboro CRS (3203), Greensboro
3201 Chapel Hill CRS, Chapel Hill
The Ponce de Leon Center CRS (5802), Atlanta
31788 Alabama CRS, Birmingham
The Ohio State Univ. AIDS CRS (2301), Columbus
Univ. of Cincinnati CRS (2401), Cincinnati
Northwestern University CRS (2701), Chicago
Rush Univ. Med. Ctr. ACTG CRS (2702), Chicago
Washington University CRS (2101), St Louis
31443 Trinity Health and Wellness Center CRS, Dallas
31473 Houston AIDS Research Team (HART) CRS, Houston
Harbor-UCLA Med. Ctr. CRS (603), Torrance
Ucsd, Avrc Crs (701), San Diego
University of Washington AIDS CRS (1401), Seattle
Hospital Nossa Senhora da Conceicao CRS (12201), Porto Alegre
Massachusetts General Hospital ACTG CRS (101), Boston
Brigham and Women's Hosp. ACTG CRS (107), Boston
31786 New Jersey Medical School Clinical Research Center CRS, Newark
The Miriam Hosp. ACTG CRS (2951), Providence
Malawi CRS (12001), Lilongwe
San Miguel CRS (11302), San Isidro
Milton Park CRS (30313), Harare
National Institute of Allergy and Infectious Diseases (NIAID)
NIH
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
NETWORK