A Cold Physical Treatment to Manage Insulin Resistance

NACompletedINTERVENTIONAL
Enrollment

33

Participants

Timeline

Start Date

July 31, 2016

Primary Completion Date

October 31, 2018

Study Completion Date

August 31, 2019

Conditions
Insulin ResistanceHyperglycemiaHyperinsulinemiaDiabetesObesity
Interventions
PROCEDURE

Selective Cold

The volunteers of intervention group will undergo Selective Cold treatment below 10 degree celsius to neck, supraclavicular interscapular regions for 2 hours daily for 8 weeks. The electroacupuncture is conducted by commercially available device. Hyperinsulinemic euglycemic clamp, glucose tolerance test, blood parameter measurements, and PTC-CT scans will be conducted before and after the intervention. The participants will be instructed to maintain their normal behavior and calorie intake.

DEVICE

Electroacupuncture

Electroacupuncture (EA) is an add-on treatment and it is applied when starting the cold treatment at the cold treated region to patients.The device is Huatuo SDZ-II model made by Suzhou Medical Appliance Factory, China.

Trial Locations (1)

710061

First Affiliated Hospital of Xi'an Jiaotong University, Xi’an

All Listed Sponsors
collaborator

Columbia University

OTHER

lead

First Affiliated Hospital Xi'an Jiaotong University

OTHER

NCT02852759 - A Cold Physical Treatment to Manage Insulin Resistance | Biotech Hunter | Biotech Hunter