Effects of Dexmedetomidine as Adjunct to Pudendal Block for Pediatric Penile Surgery

PHASE4CompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

June 17, 2016

Primary Completion Date

March 24, 2017

Study Completion Date

March 24, 2017

Conditions
Elective Penile SurgeriesHypospadiasUrethral Fistula or Stricture After Hypospadias RepairPenile Curvature
Interventions
DRUG

Dexmedetomidine

Patients are put in lithotomy position. Two separate injection points are marked at 3 and 9 o'clock, about 2 to 2.5 cm from the center of anus. After aseptic preparation, a nerve stimulator needle advanced 1.5 to 3.5 cm perpendicular to the skin, and stimulation current is 2.5 to 5 mA. The unilateral contraction of anal sphincter means the inferior anal nerve stimulation. After reducing the current to 0.5 mA, the needle is then moved deeper until an up-and-down penile movement is observed. This is stimulation of the perineal branch of the pudendal nerve. Prepared drug (0.25% ropivacaine and 0.3 mcg/kg dexmedetomidine in the experimental group, and equivalent doses of ropivacaine and normal saline in the control group) is injected in half and half bilaterally.

DRUG

plain ropivacaine

ropivacaine and normal saline equivalent doses of dexmedetomidine

DRUG

Ropivacaine

Trial Locations (1)

03722

Department of Anaesthesiology and Pain Medicine, Anaesthesia and Pain Research Institute, Yonsei University College of Medicine, Seoul

All Listed Sponsors
lead

Yonsei University

OTHER

NCT02848157 - Effects of Dexmedetomidine as Adjunct to Pudendal Block for Pediatric Penile Surgery | Biotech Hunter | Biotech Hunter