A Study of SIMPONI® to Arrest Beta-cell Loss in Type 1 Diabetes

PHASE2CompletedINTERVENTIONAL
Enrollment

84

Participants

Timeline

Start Date

August 26, 2016

Primary Completion Date

May 21, 2019

Study Completion Date

January 5, 2021

Conditions
Diabetes Mellitus, Type 1
Interventions
BIOLOGICAL

Golimumab

Participants will receive subcutaneous golimumab intermittently for 52 weeks in double-blind period, where doses will be based on weight and/or body surface area. Participants meeting response criteria at Week 52, may receive golimumab SC for 50 weeks (doses will be based on weight and/or body surface area) in an OL extension period.

BIOLOGICAL

Placebo

Matching Placebo to golimumab.

Trial Locations (33)

Unknown

Little Rock

Newport Beach

Sacramento

San Diego

San Francisco

Walnut Creek

Aurora

New Haven

Doral

Gainesville

Atlanta

Columbus

Boise

Chicago

Indianapolis

Lexington

Louisville

Baton Rouge

Baltimore

Boston

Worcester

Morristown

Buffalo

The Bronx

Mentor

Philadelphia

Sioux Falls

Dallas

San Antonio

Schertz

Webster

Seattle

Tacoma

All Listed Sponsors
lead

Janssen Research & Development, LLC

INDUSTRY

NCT02846545 - A Study of SIMPONI® to Arrest Beta-cell Loss in Type 1 Diabetes | Biotech Hunter | Biotech Hunter