Effect of KNO3 Compared to KCl on Oxygen UpTake in Heart Failure With Preserved Ejection Fraction (KNO3CK OUT HFPEF)

PHASE2CompletedINTERVENTIONAL
Enrollment

84

Participants

Timeline

Start Date

August 31, 2016

Primary Completion Date

August 31, 2022

Study Completion Date

August 31, 2022

Conditions
Heart Failure
Interventions
DRUG

Potassium Nitrate (KNO3)

The effect of potassium nitrate (KNO3) supplementation on exercise capacity and peak oxygen consumption in HFpEF will be assessed.

DRUG

Potassium Chloride (KCl)

Potassium Chloride (KCl) is the matching placebo control drug in this trial.

Trial Locations (3)

19104

Corporal Michael J Crescenz Veterans Affairs Medical Center (VA), Philadelphia

Hospital of the University of Pennsylvania, Philadelphia

60208

Northwestern Medical Center, Evanston

All Listed Sponsors
collaborator

Northwestern University

OTHER

lead

University of Pennsylvania

OTHER

NCT02840799 - Effect of KNO3 Compared to KCl on Oxygen UpTake in Heart Failure With Preserved Ejection Fraction (KNO3CK OUT HFPEF) | Biotech Hunter | Biotech Hunter