Effect of Rifampicin on the Pharmacokinetics of Apatinib

PHASE1CompletedINTERVENTIONAL

Enrollment

Participants

Timeline

Start Date

May 31, 2016

Primary Completion Date

February 28, 2017

Study Completion Date

February 28, 2017

Conditions

Neoplasms

Interventions

DRUG

Apatinib Mesylate Tablets

apatinib was administered in the morning after an overnight fast of at least 10 h

DRUG

Rifampicin Capsules

rifampicin was administered in the morning 2 hours after breakfast

Trial Locations (1)

Shanghai Xuhui Central Hospital, Shanghai

All Listed Sponsors

lead

Jiangsu HengRui Medicine Co., Ltd.

INDUSTRY

NCT02836821 - Effect of Rifampicin on the Pharmacokinetics of Apatinib | Biotech Hunter | Biotech Hunter