Efficacy and Safety of Ilaprazole Based Bismuth-containing Quadruple Regimen for the First-line Treatment of Helicobacter Pylori Infection

PHASE4CompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

June 30, 2013

Primary Completion Date

July 31, 2015

Conditions
Helicobacter Pylori Eradication Antibiotic
Interventions
DRUG

Ilaprazole antisecretory drug of each quadruple therapy the Ilaprazole -based quadruple therapy

Ilaprazole -based quadruple therapy for 14 days: Ilaprazole 5mg bid, Bismuth Potassium Citrate 220mg bid, amoxicillin 1000mg bid, clarithromycin 500mg bid

DRUG

Esoprazole antisecretory drug of each quadruple therapy Esoprazole-based quadruple therapy

Esoprazole -based quadruple therapy for 14 days: Esoprazole 20mg bid, Bismuth Potassium Citrate 220mg bid, Amoxicillin 1000mg bid, Clarithromycin 500mg bid

All Listed Sponsors
collaborator

Fifth Affiliated Hospital, Sun Yat-Sen University

OTHER

lead

Livzon Pharmaceutical Group Inc.

INDUSTRY