The Effect of Caffeine on the Narcoleptic Patients

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

16

Participants

Timeline

Start Date

October 1, 2016

Primary Completion Date

May 11, 2017

Study Completion Date

May 7, 2018

Conditions
Narcolepsy
Interventions
DRUG

Vivarin

Adenosine is an endogenous sleep-promoting substance with neuronal inhibitory effects. Adenosine has been proposed to be a sleep-inducing substance accumulating in the brain during prolonged wakefulness. Caffeine is an adenosine receptor antagonist. It inhibits a part of the sleep cycle and, in turn, promotes the wakeup state. Caffeine results in the release of norepinephrine, dopamine and serotonin in the brain and the increase of circulating catecholamines, consistent with reversal of the inhibitory effect of adenosine.Vivarin Drug class :Central nervous system (CNS) stimulants.

DRUG

Fiber

Fiber will be used as placebo.

Trial Locations (1)

Unknown

King Khalid University Hospital:King Saud Medical City, Riyadh

All Listed Sponsors
collaborator

King Saud Medical City

OTHER_GOV

lead

King Saud University

OTHER

NCT02832336 - The Effect of Caffeine on the Narcoleptic Patients | Biotech Hunter | Biotech Hunter