Using Biomarkers to Predict TB Treatment Duration

PHASE2CompletedINTERVENTIONAL
Enrollment

946

Participants

Timeline

Start Date

June 21, 2017

Primary Completion Date

October 9, 2021

Study Completion Date

February 28, 2022

Conditions
Pulmonary Tuberculosis
Interventions
PROCEDURE

Saliva collection

For biomarker assessments

PROCEDURE

Urine collection

For biomarker assessments

PROCEDURE

Sputum collection

For primary endpoint assessments and other biomarker assessments

PROCEDURE

Blood Collection

For biomarker and eligibility assessments

RADIATION

PET/CT Scan

Imaging of the lungs to establish disease extent and severity

DRUG

Isoniazid, Rifampicin, Pyrazinamide and Ethambutol

Treatment-standard of care

Trial Locations (1)

Unknown

Clinical Infectious Diseases Research Initiative (Khayelitsha site), Cape Town

All Listed Sponsors
lead

National Institute of Allergy and Infectious Diseases (NIAID)

NIH

NCT02821832 - Using Biomarkers to Predict TB Treatment Duration | Biotech Hunter | Biotech Hunter