Postprandial Metabolism After Bariatric Surgery in Type 2 Diabetes

NACompletedINTERVENTIONAL
Enrollment

18

Participants

Timeline

Start Date

August 31, 2015

Primary Completion Date

December 31, 2019

Study Completion Date

December 31, 2019

Conditions
Type 2 DiabetesObese
Interventions
PROCEDURE

biliopancreatic diversion with duodenal switch

PROCEDURE

sleeve gastrectomy

OTHER

liquid meal

will be consumed over 30 minutes with \[U-13C\]-palmitate (0.2 g mixed in the liquid meal) and H2-glucose

RADIATION

PET/scan

a dynamic and whole body PET acquisition will be performed on a thoraco-abdominal segment, 150 minutes after an oral administration of 18FTHA

OTHER

[7,7,8,8-2H]-palmitate

i.v. administration of \[7,7,8,8-2H\]-palmitate (in 25% human albumin) from time -60 to 360 min.

DEVICE

indirect calorimetry

will be performed every hour throughout the protocol along with exhaled breath collection

Trial Locations (1)

J1H 5N4

Centre de recherche du CHUS, Sherbrooke

All Listed Sponsors
collaborator

Laval University

OTHER

lead

Université de Sherbrooke

OTHER

NCT02815943 - Postprandial Metabolism After Bariatric Surgery in Type 2 Diabetes | Biotech Hunter | Biotech Hunter