296
Participants
Start Date
September 13, 2016
Primary Completion Date
November 17, 2021
Study Completion Date
December 19, 2021
Aerobic exercise
Moderate/high intensity aerobic exercise will involve training at 70-80% heart rate reserve for 30 min, with an additional 10 minutes for warm-up and 5 minutes for cool-down, 4 times per week, for 12 months while supervised twice per week by a study-certified trainer at a participating YMCA .
Stretching/balance/range of motion exercise
The stretching/balance/range of motion program will involve exercise at or below 35% heart rate reserve for 30 min, with an additional 10 minutes for warm up and 5 minutes for cool-down, 4 times per week, for 12 months while supervised twice per week by a study-certified trainer at a participating YMCA.
New York University Medical Center, New York
Mount Sinai School of Medicine, New York
Wake Forest University Health Sciences, Winston-Salem
Duke University, Durham
Emory University, Atlanta
University of Kentucky, Lexington
University of Wisconsin, Madison
Great Lakes Clinical Trials (Andersonville), Chicago
University of Kansas Medical Center, Kansas City
University of North Texas Health Science Center, Fort Worth
Cleveland Clinic Lou Ruvo Center for Brain Health, Las Vegas
University of California, Irvine, Irvine
VAPAHCS / Stanford University School of Medicine, Palo Alto
Yale University School of Medicine, New Haven
National Institute on Aging (NIA)
NIH
Wake Forest University Health Sciences
OTHER
Alzheimer's Disease Cooperative Study (ADCS)
OTHER