A Study of Atezolizumab Compared With Docetaxel in Non-Small Cell Lung Cancer (NSCLC) After Failure With Platinum-Containing Chemotherapy

PHASE3CompletedINTERVENTIONAL
Enrollment

565

Participants

Timeline

Start Date

July 1, 2016

Primary Completion Date

August 1, 2019

Study Completion Date

December 27, 2022

Conditions
Carcinoma, Non-Small-Cell Lung
Interventions
DRUG

Atezolizumab (MPDL3280A), an engineered anti-PD-L1 antibody

Atezolizumab will be administered at a fixed dose of 1200 milligrams (mg) via intravenous (IV) infusion on Day 1 of each 21-day cycle.

DRUG

Docetaxel

Docetaxel will be administered as 75 milligrams per square meter (mg/m\^2) via IV infusion on Day 1 of each 21-day cycle.

Trial Locations (38)

10330

Chulalongkorn Hospital; Medical Oncology, Bangkok

10400

Ramathibodi Hospital; Dept of Med.-Div. of Med. Onc, Bangkok

10700

Faculty of Med. Siriraj Hosp.; Med.-Div. of Med. Oncology, Bangkok

35015

Chungnam National University Hospital, Daejeon

41404

Kyungpook National University Medical Center, Daegu

50200

CHIANG MAI UNI HOSPITAL; FACULTY OF MEDICINE; Medical Oncology unit, Chiang Mai

50586

Hospital Kuala Lumpur; Jabatan Radioterapi dan Onkologi, Kuala Lumpur

58128

Chonnam National University Hwasun Hospital, Jeollanam-do

81100

Hospital Sultan Ismail; Oncology, Johor Bahru

93586

Sarawak General Hospital; Department of Radiotherapy, Oncology and Palliative care, Sarawak

100021

Cancer Hospital Chinese Academy of Medical Sciences., Beijing

100142

Beijing Cancer Hospital, Beijing

101149

Beijing Chest Hospital; Oncology Department, Beijing

110042

Liaoning cancer Hospital & Institute, Shenyang

130021

the First Hospital of Jilin University, Changchun

132013

Jilin Cancer Hospital, Changchun

150081

Harbin Medical University Cancer Hospital, Harbin

169610

National Cancer Centre; Medical Oncology, Singapore

200030

Shanghai chest hospital, Shanghai

200032

Zhongshan Hospital Fudan University, Shanghai

200120

Fudan University Shanghai Cancer Center, Shanghai

211100

Jiangsu Cancer Hospital, Nanjing

213003

Changzhou First People's Hospital, Changzhou

233004

Affiliated Hospital of Bengbu Medical College, Bengbu

266003

The Affiliated Hospital of Medical College Qingdao University, Qingdao

300052

Tianjin Medical University General Hospital, Tianjin

310003

The First Affiliated Hospital of College of Medicine, Zhejiang University, Hangzhou

310018

Sir Run Run Shaw Hospital, Hangzhou

310022

Zhejiang Cancer Hospital, Zhejiang

400030

Second Affiliated Hospital of Third Military Medical University, Chongqing

400042

Third Affiliated Hospital of Third Military Medical University, Chongqing

450008

Henan Cancer Hospital, Zhengzhou

510080

Guangdong General Hospital, Guangzhou

510120

The First Affiliated Hospital of Guangzhou Medical University, Guangzhou

510663

Sun Yet-sen University Cancer Center, Guangzhou

610041

West China Hospital, Sichuan University, Chengdu

710061

The First Affiliated Hospital of Xian Jiao Tong University, Xi'an

08308

Korea University Guro Hospital, Seoul

All Listed Sponsors
lead

Hoffmann-La Roche

INDUSTRY

NCT02813785 - A Study of Atezolizumab Compared With Docetaxel in Non-Small Cell Lung Cancer (NSCLC) After Failure With Platinum-Containing Chemotherapy | Biotech Hunter | Biotech Hunter