Deep Versus Moderate Neuromuscular Blockade During Laparoscopic Surgery

PHASE4CompletedINTERVENTIONAL
Enrollment

79

Participants

Timeline

Start Date

December 27, 2016

Primary Completion Date

January 17, 2019

Study Completion Date

February 6, 2019

Conditions
CholecystitisEndometriosisBowel ObstructionFibroidsProstate CancerChronic Kidney DiseaseUterine Prolapse
Interventions
PROCEDURE

Deep to Moderate NMB

"Rocuronium infusion will be paused and the Train of Four (TOF) monitor will be set to every 1-2 min. Once the patient has achieved a moderate NMB state (one to two twitches), the infusion of the muscle relaxant will be resumed at a low dose to maintain the patient at this level of blockade."

PROCEDURE

Moderate to Deep NMB

"Rocuronium infusion will be increased in increments of 0.1-0.2 mg/kg/hr. and the TOF monitor will be set to every 1-2 min. Once the patient has no twitches and a PTC of 0-1 (deep NMB) the infusion will be adjusted to maintain the patient at this level of NMB."

DRUG

Rocuronium

Trial Locations (1)

11794

Stony Brook University Hospital, Stony Brook

All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

lead

Stony Brook University

OTHER

NCT02812186 - Deep Versus Moderate Neuromuscular Blockade During Laparoscopic Surgery | Biotech Hunter | Biotech Hunter