60
Participants
Start Date
September 30, 2015
Primary Completion Date
February 29, 2016
Study Completion Date
June 30, 2016
dexmedetomidine
A loading dose dexmedetomidine (0.5 ug/kg IV infused in 15 minutes) will be administered after anesthesia induction, followed by a continuous infusion at a rate of 0.5 ug/kg/h until the closure of the brain duramater at the end of surgery.
normal saline
Normal saline will be administered in the same rate, volume and duration as that in the dexmedetomidine group
Department of Anesthesiology and Critical Care Medicine, Peking University First Hospital, Beijing
Beijing Tiantan Hospital
OTHER
Peking University First Hospital
OTHER