121
Participants
Start Date
June 30, 2016
Primary Completion Date
July 27, 2021
Study Completion Date
March 4, 2022
Exposure-based therapy
Exposure-based therapy
Behavioral Activation therapy
Behavioral Activation therapy
Computer-based behavioral assessment
Computer-based tasks during which participants respond to images on the screen, including abstract images, emotional faces, and pleasant and unpleasant images.
Surveys and Interviews
Surveys and interviews in which participants will be asked to answer questions related to their mental and physical health history and current symptoms.
Magnetic resonance imaging (MRI)
Magnetic resonance imaging (MRI) will be used to obtain information concerning the structure of the brain, as well as to assess changes associated with blood flow in the brain while participants are completing behavioral tasks (see description of computer-based behavioral assessment intervention).
Electroencephalography (EEG)
Electroencephalography (EEG) will be used to assess changes in the electrical activity of the brain while participants are completing behavioral tasks (see description of computer-based behavioral assessment intervention).
Laureate Institute for Brain Research, Tulsa
Lead Sponsor
National Institute of Mental Health (NIMH)
NIH
Laureate Institute for Brain Research, Inc.
OTHER