NCT02807428View on ClinicalTrials.gov

Study to Evaluate Safety/Efficacy of a Single Preop Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery

PHASE2CompletedINTERVENTIONAL
Enrollment

210

Participants

Timeline

Start Date

February 20, 2017

Primary Completion Date

October 23, 2017

Study Completion Date

December 19, 2017

Conditions
Post-surgical Pain
Interventions
DRUG

AYX1 Injection 660 mg/6 mL

6 mL solution for intrathecal injection with 660 mg of AYX1 (Brivoligide)

DRUG

Placebo Injection 6 mL

6 mL solution for intrathecal injection; vehicle formulation designed to mimic AYX1 Injection (with no active drug)

Trial Locations (9)

15701

Antria, Inc., Indiana

32503

Pensacola Research Consultants, Pensacola

33321

Phoenix Clinical Research, Tamarac

35209

Alabama Orthopedic Center, Birmingham

35660

Shoals Medical Trials, Sheffield

39202

Mississippi Sports Medicine, Jackson

43210

The Ohio State University Wexner Medical Center, Columbus

85023

Arizona Research Center, Phoenix

92024

CORE Orthopaedic Medical Center, Encinitas

All Listed Sponsors
lead

Adynxx, Inc.

INDUSTRY

NCT02807428 - Study to Evaluate Safety/Efficacy of a Single Preop Dose of AYX1 Injection to Treat Pain After Knee Replacement Surgery | Biotech Hunter | Biotech Hunter