Psychopathological Differences Between Asperger Syndrome and Schizotypal Disorder in an Adult Sample

CompletedOBSERVATIONAL
Enrollment

59

Participants

Timeline

Start Date

June 30, 2016

Primary Completion Date

December 31, 2018

Study Completion Date

December 31, 2018

Conditions
Asperger SyndromeAutism Spectrum DisorderSchizotypal Personality Disorder
Interventions
OTHER

Expert panel evaluation

"From the medical records, described social and psychiatric history and observed psychiatric symptoms will be summarized and presented to two senior psychiatric consultants. The panels evaluation ensures the identification of subjects with typical symptoms, according to a best estimate clinical consensus.~The panel divides the participants into 4 groups: 'participant with symptoms typical of AS', 'participant with symptoms typical of SD', 'participant with inconclusive/non typical symptoms' and 'non eligible participant'."

OTHER

Semi-structured psychopathological interviews

Included participants are asked for a detailed social and developmental history and interviewed with 3 semi-structured interviews: 1. Schedules for Assessment in Neuropsychiatry (SCAN); Covering psychopathology and behaviour associated with the major psychiatric disorders. 2. Autism Diagnostic Observation Schedule (ADOS), module 4; An assessment to identify symptoms within the autism spectrum. 3. Examination of anomalous self-experience (EASE); A checklist for exploration of experiential anomalies. The Ph.D.-student will obtain social and developmental history and carry out SCAN and EASE interviews. ADOS will be carried out by a consultant psychologist at The Danish Autism Centre.

OTHER

Self-administered rating scales

1.The Autism Quotient (AQ), a 50 question scale, for the assessment of autistic traits, 2. The Schizotypal Personality Questionnaire (SPQ), a 74 item scale, for the assessment of schizotypal personality, 3. The WHO-5 Well-Being Index (WHO-5), a 5 item scale, for the assessment of subjective psychological well-being.

OTHER

Other general interviewer ratings

1\. Global Assessment of Functioning (GAF), a numeric scale (1 through 100) for assessing social, occupational, and psychological functioning, 2. The Clinical Global Impressions scale (CGI-Severity), an assessment of the clinician's global view of the patient's severity of psychopathology on a 7 point scale.

Trial Locations (2)

2730

The Danish Autism Centre, Herlev

2750

Mental Health Centre Ballerup, Mental Health Services, The Capitol Region, Copenhagen, Ballerup Municipality

All Listed Sponsors
collaborator

The Danish Autism Centre

UNKNOWN

lead

Mental Health Services in the Capital Region, Denmark

OTHER

NCT02800681 - Psychopathological Differences Between Asperger Syndrome and Schizotypal Disorder in an Adult Sample | Biotech Hunter | Biotech Hunter