A Phase 1/2 Trial of SRA737 in Subjects With Advanced Cancer

PHASE1/PHASE2CompletedINTERVENTIONAL
Enrollment

107

Participants

Timeline

Start Date

July 31, 2016

Primary Completion Date

October 28, 2019

Study Completion Date

October 28, 2019

Conditions
Advanced Solid Tumors or Non-Hodgkin's Lymphoma (NHL)
Interventions
DRUG

SRA737

SRA737 will be administered orally on each day of a 28-day cycle. Subjects will receive a single dose of SRA737 between 4 to 7 days prior to starting the first cycle for PK profiling. Subjects can continue taking SRA737 if they are receiving clinical benefit and able to safely take the drug and follow the requirements of the study.

Trial Locations (15)

SM2 5PT

Royal Marsden Hospital, Sutton

BT9 7AB

Belfast City Hospital, Belfast

OX3 7LE

Oxford University Hospitals, Headington

CF14 2TL

Velindre Cancer Centre - Cardiff, Cardiff

CH63 4JY

The Clatterbridge Cancer Centre, Bebington

EH4 2XU

Western General Hospital, Edinburgh

G12 0YN

The Beatson West of Scotland Cancer Centre, Glasgow

LS9 7TF

The Leeds Teaching Hospitals of St James University Hospital, Leeds

LE1 5WW

University Hospitals of Leicester, Leicester

SE1 9RT

Guy's and St. Thomas, London

W1G 6AD

Sarah Cannon Research Institute, London

W1T 7HA

University College London Hospitals, London

M20 4BX

The Christie, Manchester

NE7 7DN

Freeman Hospital, Newcastle upon Tyne

S10 2SJ

Sheffield Teaching Hospitals, Sheffield

All Listed Sponsors
lead

Sierra Oncology LLC - a GSK company

INDUSTRY

NCT02797964 - A Phase 1/2 Trial of SRA737 in Subjects With Advanced Cancer | Biotech Hunter | Biotech Hunter