NCT02797717View on ClinicalTrials.gov

Treatment for Classical Hodgkin Lymphoma in Children and Adolescents

NARecruitingINTERVENTIONAL
Enrollment

2,200

Participants

Timeline

Start Date

November 30, 2015

Primary Completion Date

December 31, 2022

Study Completion Date

December 31, 2027

Conditions
Classical Hodgkins Lymphoma in Children and Adolescents.
Interventions
RADIATION

Radiotherapy:

"All patients will have 2 OPEAcycles(chemotherapy cycle:Vincristine,Etoposide,Prednisone,doxorubicin) ,After assignment ( by randomization) to one of the arms the patient will be treated accordingly . response assessment will be done after OPEA cycles (ERA) and after cycles of copdac 28 or DECOPDAC 21(LRA).according to the assessments results patients will have radiotherapy or not."

DRUG

Vincristine

ARM A and ARM B

DRUG

Etoposide

ARM B , 100mg/m2/day

DRUG

Prednisone

ARM A and ARM B , 40mg/m2/day p.o

DRUG

Doxorubicin

ARM B , 25mg/m2

DRUG

Dacarbazine

ARM A and ARM B , 250mg/m2 i.v

DRUG

Cyclophosphamide

ARM A and ARM B , 625mg/m2 i.v

Trial Locations (1)

4920235

RECRUITING

Schneider children's medical center, Petah Tikva

All Listed Sponsors
collaborator

University of Giessen

OTHER

lead

GALIA AVRAHAMI

OTHER