Tremelimumab and Durvalumab in Combination or Alone in Treating Patients With Recurrent Malignant Glioma

PHASE2CompletedINTERVENTIONAL
Enrollment

36

Participants

Timeline

Start Date

November 1, 2016

Primary Completion Date

May 9, 2018

Study Completion Date

June 17, 2020

Conditions
Malignant GliomaRecurrent Glioblastoma
Interventions
BIOLOGICAL

Durvalumab

Given IV

OTHER

Laboratory Biomarker Analysis

Correlative Studies

PROCEDURE

Surgical Procedure

Undergo surgical tumor resection

BIOLOGICAL

Tremelimumab

Given IV

Trial Locations (1)

60611

Northwestern University, Chicago

Sponsors

Collaborators (2)

All Listed Sponsors
collaborator

AstraZeneca

INDUSTRY

collaborator

MedImmune LLC

INDUSTRY

collaborator

National Cancer Institute (NCI)

NIH

lead

Northwestern University

OTHER