Hybrid Closure of Congenital Heart Disease

NACompletedINTERVENTIONAL
Enrollment

200

Participants

Timeline

Start Date

January 31, 2011

Primary Completion Date

December 31, 2016

Study Completion Date

December 31, 2016

Conditions
Pediatric Ventricular Septal Defects
Interventions
DRUG

sufentanil anesthesia

Anaesthesia is maintained by inhaled isoflurane in concentrations 0.7-0.8 % end-tidal with additional sufentanil injected during surgery, as required. During extracorporal circulation patients receive isoflurane via a vaporizer incorporated in the extracorporeal gas supply in the same concentrations.

PROCEDURE

Hybrid closure

Hybrid closure of ventricular septal defects through the delivery system without cardiopulmonary bypass by transthoracic minimally invasive small incision.

PROCEDURE

Control

Surgical closure of ventricular septal defects with cardiopulmonary bypass by routine open thoracotomy.

Sponsors
All Listed Sponsors
lead

Nanjing Medical University

OTHER