200
Participants
Start Date
January 31, 2011
Primary Completion Date
December 31, 2016
Study Completion Date
December 31, 2016
sufentanil anesthesia
Anaesthesia is maintained by inhaled isoflurane in concentrations 0.7-0.8 % end-tidal with additional sufentanil injected during surgery, as required. During extracorporal circulation patients receive isoflurane via a vaporizer incorporated in the extracorporeal gas supply in the same concentrations.
Hybrid closure
Hybrid closure of ventricular septal defects through the delivery system without cardiopulmonary bypass by transthoracic minimally invasive small incision.
Control
Surgical closure of ventricular septal defects with cardiopulmonary bypass by routine open thoracotomy.
Lead Sponsor
Nanjing Medical University
OTHER