296
Participants
Start Date
August 31, 2015
Primary Completion Date
June 29, 2017
Study Completion Date
June 29, 2017
propofol
For patients in Group P, the sedation was achieved with a target-controlled infusion (TCI) of propofol, and the effect site concentration was set to 0.8-1.0μg/ml.
dexmedetomidine
For patients in Group D, the sedation was achieved with a bolus of dexmedetomidine at 1.0 μg/kg (over a period of 15 to 20 min) and followed by an infusion of dexmedetomidine at 0.2-0.7 μg/kg/h. The depth of sedation was considered enough when patient was unresponsive to voice.
The first affiliated hospital of Anhui Medical University, Hefei
The First Affiliated Hospital of Anhui Medical University
OTHER