Dexmedetomidine vs Propofol Sedation Reduces Postoperative Delirium in Patients Receiving Hip Arthroplasty.

NACompletedINTERVENTIONAL
Enrollment

296

Participants

Timeline

Start Date

August 31, 2015

Primary Completion Date

June 29, 2017

Study Completion Date

June 29, 2017

Conditions
AnesthesiaLocal Anesthesia
Interventions
DRUG

propofol

For patients in Group P, the sedation was achieved with a target-controlled infusion (TCI) of propofol, and the effect site concentration was set to 0.8-1.0μg/ml.

DRUG

dexmedetomidine

For patients in Group D, the sedation was achieved with a bolus of dexmedetomidine at 1.0 μg/kg (over a period of 15 to 20 min) and followed by an infusion of dexmedetomidine at 0.2-0.7 μg/kg/h. The depth of sedation was considered enough when patient was unresponsive to voice.

Trial Locations (1)

230022

The first affiliated hospital of Anhui Medical University, Hefei

All Listed Sponsors
lead

The First Affiliated Hospital of Anhui Medical University

OTHER

NCT02793986 - Dexmedetomidine vs Propofol Sedation Reduces Postoperative Delirium in Patients Receiving Hip Arthroplasty. | Biotech Hunter | Biotech Hunter