Efficacy of Peri-Incisional Multimodal Drug Injection Following Operative Management of Femur Fractures

PHASE4CompletedINTERVENTIONAL
Enrollment

102

Participants

Timeline

Start Date

May 31, 2015

Primary Completion Date

August 31, 2016

Study Completion Date

August 31, 2016

Conditions
Pain, PostoperativeFemur Fracture
Interventions
DRUG

Ropivacaine

400 mg of 0.75% ropivacaine (53.33 mL) will be included in the multimodal analgesic cocktail that will be injected intra-operatively into the superficial and deep peri-incisional tissues after completion of femur fracture fixation/instrumentation.

DRUG

Epinephrine

0.6 mg of 1 mg/mL epinephrine (0.6 mL) will be included in the multimodal analgesic cocktail that will be injected intra-operatively into the superficial and deep peri-incisional tissues after completion of femur fracture fixation/instrumentation.

DRUG

Morphine

5 mg of 0.5 mg/mL morphine sulfate (10 mL) will be included in the multimodal analgesic cocktail that will be injected intra-operatively into the superficial and deep peri-incisional tissues after completion of femur fracture fixation/instrumentation.

DRUG

0.9% sodium chloride solution

36.07 mL 0.9% sodium chloride solution will be included in the multimodal analgesic cocktail that will be injected intra-operatively into the superficial and deep peri-incisional tissues after completion of femur fracture fixation/instrumentation.

Trial Locations (1)

52242

University of Iowa Hospitals and Clinics, Iowa City

All Listed Sponsors
lead

University of Iowa

OTHER

NCT02793947 - Efficacy of Peri-Incisional Multimodal Drug Injection Following Operative Management of Femur Fractures | Biotech Hunter | Biotech Hunter