The OLYMPUS Study - Optimized DeLivery of Mitomycin for Primary UTUC Study

PHASE3CompletedINTERVENTIONAL
Enrollment

71

Participants

Timeline

Start Date

April 4, 2017

Primary Completion Date

April 5, 2019

Study Completion Date

March 5, 2020

Conditions
Carcinoma, Transitional CellTransitional Cell Carcinoma of Renal Pelvis
Interventions
DRUG

UGN-101 instillations

Treatment with UGN-101 once weekly for a total of 6 times; in a retrograde fashion. Patients who will demonstrate complete response (CR) will be treated with UGN-101 once monthly as a maintenance therapy for a total of 11 instillations or up to the first recurrence whichever comes first.

Trial Locations (24)

10065

Memorial Sloan Kettering Cancer Center, New York

Weill Cornell Medical Center, New York

10467

Montefiore Medical Center (Albert Einstein), The Bronx

17033

Penn State College of Medicine, Hershey

19107

Thomas Jefferson University Hospitals, Philadelphia

21218

John Hopkins University, Baltimore

27514

University of north carolina - chapel hill, Chapel Hill

32224

Mayo Clinic Florida, Jacksonville

43210

The Ohio State University Wexner Medical Center, Columbus

46202

Indiana University School of Medicine, Indianapolis

48109

University of Michigan Comprehensive Cancer Center, Ann Arbor

49372

Hasharon Hospital (Rabin Medical Center), Petah Tikva

52621

Sheba Medical Center, Ramat Gan

55455

University of Minnesota, Minneapolis

55905

Mayo Clinic health system, Rochester

60153

Loyola University Medical Center, Department of Urology, Maywood

77006

MD Anderson, Houston

77030

Baylor College of Medicine, Houston

85054

Mayo Clinic Hospital, Phoenix

89144

Urology Center Las Vegas, Las Vegas

90095

University of California, Los Angeles

90404

Providence Medical Institute, Santa Monica

92354

Loma Linda Cancer Center, Loma Linda

98109--1023

Seattle Cancer Care Alliance (University of Washington), Seattle

All Listed Sponsors
lead

UroGen Pharma Ltd.

INDUSTRY

NCT02793128 - The OLYMPUS Study - Optimized DeLivery of Mitomycin for Primary UTUC Study | Biotech Hunter | Biotech Hunter