815
Participants
Start Date
August 31, 2015
Primary Completion Date
March 31, 2021
Study Completion Date
March 31, 2021
Cardiovascular Magnetic Resonance Imaging (CMRI)
CMRI uses interaction of the magnetic properties of body tissues with strong magnetic fields to create images; for about 1 hour. Several sets of images are needed. No injection of drug or dye will be used for this procedure.
Electrocardiogram (ECG)
ECG is a non-invasive test used to detect any underlying heart conditions by measuring the electrical activity of the heart.
Blood Sample Collection
Blood will be drawn for circulating biomarkers, which are measurable indicators of the severity or presence of the heart failure condition.
Clinical Assessment
Check health status, blood pressure, heart rate, height and weight measured. In addition, subject will undergo a heart examination.
Cardiovascular Ultrasound (CVUS)
To measure heart chamber size, heart function, blood vessel size and blood vessel function. These measurements will help the investigators understand the type and severity of heart failure.
Cognitive Test
To relate the presence and severity of cognitive impairment (CI) with simultaneously acquired advanced cardiovascular imaging characteristics and circulating biomarkers of cardiovascular function, inflammation and coagulation.
National Heart Centre Singapore, Singapore
Singapore General Hospital
OTHER
National University Hospital, Singapore
OTHER
Tan Tock Seng Hospital
OTHER
Khoo Teck Puat Hospital
OTHER
Changi General Hospital
OTHER
National Heart Centre Singapore
OTHER