"Asian neTwork for Translational Research and Cardiovascular Trials (ATTRaCT)"

CompletedOBSERVATIONAL
Enrollment

815

Participants

Timeline

Start Date

August 31, 2015

Primary Completion Date

March 31, 2021

Study Completion Date

March 31, 2021

Conditions
Heart Failure
Interventions
OTHER

Cardiovascular Magnetic Resonance Imaging (CMRI)

CMRI uses interaction of the magnetic properties of body tissues with strong magnetic fields to create images; for about 1 hour. Several sets of images are needed. No injection of drug or dye will be used for this procedure.

OTHER

Electrocardiogram (ECG)

ECG is a non-invasive test used to detect any underlying heart conditions by measuring the electrical activity of the heart.

OTHER

Blood Sample Collection

Blood will be drawn for circulating biomarkers, which are measurable indicators of the severity or presence of the heart failure condition.

OTHER

Clinical Assessment

Check health status, blood pressure, heart rate, height and weight measured. In addition, subject will undergo a heart examination.

OTHER

Cardiovascular Ultrasound (CVUS)

To measure heart chamber size, heart function, blood vessel size and blood vessel function. These measurements will help the investigators understand the type and severity of heart failure.

OTHER

Cognitive Test

To relate the presence and severity of cognitive impairment (CI) with simultaneously acquired advanced cardiovascular imaging characteristics and circulating biomarkers of cardiovascular function, inflammation and coagulation.

Trial Locations (1)

169609

National Heart Centre Singapore, Singapore

All Listed Sponsors
collaborator

Singapore General Hospital

OTHER

collaborator

National University Hospital, Singapore

OTHER

collaborator

Tan Tock Seng Hospital

OTHER

collaborator

Khoo Teck Puat Hospital

OTHER

collaborator

Changi General Hospital

OTHER

lead

National Heart Centre Singapore

OTHER

NCT02791009 - "Asian neTwork for Translational Research and Cardiovascular Trials (ATTRaCT)" | Biotech Hunter | Biotech Hunter