A Carbohydrate-restricted Diet to Reverse Fatty Liver in Adolescents With Obesity

NACompletedINTERVENTIONAL
Enrollment

27

Participants

Timeline

Start Date

May 31, 2016

Primary Completion Date

April 30, 2018

Study Completion Date

April 30, 2018

Conditions
Non-alcoholic Fatty Liver DiseaseChildhood ObesityInsulin Resistance
Interventions
OTHER

Carbohydrate-restricted diet

Participants will be randomized (20 per group) to the carbohydrate restricted diet (i.e., CHO \<10%; fat \>65%, protein 25%) or a low fat diet (CHO 55%; fat 20%; protein 25%) for 8 weeks. Individual counseling with the study physician and registered dietitian (RD) will be provided at baseline for initial assessment and diet instruction. Participants will meet with a RD for an individual counselling session at week 2, 4, and 6 of the diet intervention to ensure adherence to the diet prescription. Participants will be encouraged to keep track of dietary intake by using electronic food diaries (weeks 1-8) to review with the RD during individual counseling at week 2, week 4 and week 6.

OTHER

Control, low-fat diet

Individual counseling with the study physician and registered dietitian (RD) will be provided at baseline for initial assessment and diet instruction. Participants will meet with a RD for an individual counselling session at week 2, 4, and 6 of the diet intervention to ensure adherence to the diet prescription. Participants will be encouraged to keep track of dietary intake by using electronic food diaries (weeks 1-8) to review with the RD during individual counseling at week 2, week 4 and week 6.

Trial Locations (1)

35223

University of Alabama at Birmingham, Birmingham

All Listed Sponsors
lead

University of Alabama at Birmingham

OTHER

NCT02787668 - A Carbohydrate-restricted Diet to Reverse Fatty Liver in Adolescents With Obesity | Biotech Hunter | Biotech Hunter