Laparoscopic Surgery VS RFA for Recurrent HCC

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

340

Participants

Timeline

Start Date

December 31, 2016

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Hepatocellular Carcinoma
Interventions
PROCEDURE

laparoscopic surgery(LS)

For LS, the patient was usually placed in the lithotomy position. Pneumoperitoneum was maintained at a pressure between 12 and 14 mmHg. Three to 4 working ports sized between 5 mm and 12 mm were used . Intra-operative ultrasonography was performed routinely. Parenchymal transection was performed using a Cavitron ultrasonic surgical aspirator (CUSA, Valleylab, Boulder, CO, USA). Large bile duct branches or vessels were clipped before division and minor hemostasis was carried out using bipolar diathermy. Large hepatic vein branches were divided by endovascular staplers. A 1.0-cm safety margin was planed to get during the liver resection.

PROCEDURE

RFA

RFA was performed according to the Guidelines of Radiofrequency Ablation Therapy for Liver Cancer: Chinese Expert Consensus Statement issued by the Chinese Society of Liver Cancer and Chinese Society of Clinical Oncology RFA was performed under real-time ultrasound guidance. RFA was performed by using a commercially available Cool-tipTM RFA system (Valleylab, Boulder, CO, USA), or a RF 2000 system (Radio-Therapeutics Mountain View, CA). Grounding was achieved by attaching 2 pads to the patient's back or legs.

All Listed Sponsors
collaborator

Second Military Medical University

OTHER

lead

Sun Yat-sen University

OTHER