Pethidine Versus Nitrous Oxide for Pain Relief During Labor

NACompletedINTERVENTIONAL
Enrollment

214

Participants

Timeline

Start Date

August 31, 2016

Primary Completion Date

May 31, 2019

Study Completion Date

May 31, 2019

Conditions
Labor Pain
Interventions
DRUG

IV Meperidine

"Intravenous meperidine 50mg in 100cc NaCl 0.9% . Repeated doses (if needed): intervals of 2 hours minimum until a maximum of 4 doses.~In cases of nausea or vomiting intravenous metoclopramide 10mg will be offered to the parturient.~If pain intensity (according to visual analogue scale), 20 to 30 minutes from administration, will not decline or the parturient will ask for a different type of analgesia, inhaled nitrous oxide or epidural analgesia will be offered."

DRUG

Nitrous Oxide

"Nitrous oxide in a 50/50 mix with oxygen given via self-administered face mask. The parturient will be advised to place the mask tightly on her face and to breathe through it at the first sign of forthcoming uterine contraction. Between contractions, she will be advised not to breathe through the mask.~In cases of nausea or vomiting intravenous metoclopramide 10mg will be offered to the parturient.~If pain intensity (according to visual analogue scale), 20 to 30 minutes from administration, will not decline or the parturient will ask for a different type of analgesia, intravenous meperidine or epidural analgesia will be offered."

Trial Locations (1)

18101

HaEmek Medical Center, Afula

All Listed Sponsors
lead

HaEmek Medical Center, Israel

OTHER

NCT02783508 - Pethidine Versus Nitrous Oxide for Pain Relief During Labor | Biotech Hunter | Biotech Hunter