Remote Ischaemic Conditioning After Stroke Trial (ReCAST-2)

PHASE2CompletedINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

August 1, 2016

Primary Completion Date

July 23, 2018

Study Completion Date

July 23, 2018

Conditions
Stroke
Interventions
PROCEDURE

Remote ischaemic conditioning

1 dose (=4 cycles) of intermittent upper limb ischaemia (1 cycle = 5minutes inflation to 20mmHg above systolic BP, 5 minutes deflation). Dose escalation: (i) Recruits 1-20 receive this cycle once (ii) Recruits 21-40 receive a second dose of 4-cycles one hour after the first. (iii) Recruits 41-60 receive further dosing, twice daily until day 4.

PROCEDURE

Sham

4 cycles of intermittent sham procedure (1 cycle = 5 minutes inflation to 30 mmHg, 5 minutes deflation), matching the dose escalation described in the intervention

Trial Locations (2)

DE22 3DT

Derby Teaching Hospitals Foundation Trust, Derby

NG5 1PB

Nottingham University Hospitals NHS Trust, Nottingham

All Listed Sponsors
lead

University of Nottingham

OTHER

NCT02779712 - Remote Ischaemic Conditioning After Stroke Trial (ReCAST-2) | Biotech Hunter | Biotech Hunter