FLARE RT for Patients With Stage IIB-IIIB Non-small Cell Lung Cancer: Personalizing Radiation Therapy Using PET/CT and SPECT/CT Imaging

PHASE2CompletedINTERVENTIONAL
Enrollment

51

Participants

Timeline

Start Date

May 20, 2016

Primary Completion Date

June 1, 2023

Study Completion Date

December 1, 2023

Conditions
Stage IIB Lung Non-Small Cell Carcinoma AJCC v7Stage IIIA Lung Non-Small Cell Cancer AJCC v7Stage IIIB Lung Non-Small Cell Cancer AJCC v7
Interventions
PROCEDURE

Computed Tomography

Undergo FDG PET/CT

PROCEDURE

Computed Tomography

Undergo Tc-99m MAA or Tc-99m DTPA

RADIATION

Fludeoxyglucose F-18

Undergo FDG PET/CT

OTHER

Laboratory Biomarker Analysis

Correlative studies

PROCEDURE

Positron Emission Tomography

Undergo FDG PET/CT

RADIATION

Radiation Therapy

Undergo functional avoidance radiation therapy

PROCEDURE

Single Photon Emission Computed Tomography

Undergo Tc-99m MAA or Tc-99m Undergo Tc-99m sulfur colloid SPECT/CT

RADIATION

Technetium Tc-99m Albumin Aggregated

Undergo Tc-99m MAA SPECT/CT

RADIATION

Technetium Tc-99m Sulfur Colloid

Undergo Tc-99m sulfur colloid

Trial Locations (2)

98109

Fred Hutch/University of Washington Cancer Consortium, Seattle

98133

SCCA Proton Therapy Center, Seattle

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

University of Washington

OTHER

NCT02773238 - FLARE RT for Patients With Stage IIB-IIIB Non-small Cell Lung Cancer: Personalizing Radiation Therapy Using PET/CT and SPECT/CT Imaging | Biotech Hunter | Biotech Hunter