Shave Margins vs. Standard Partial Mastectomy in Breast Cancer Patients

NACompletedINTERVENTIONAL
Enrollment

400

Participants

Timeline

Start Date

July 31, 2016

Primary Completion Date

June 30, 2018

Study Completion Date

November 30, 2024

Conditions
Breast Cancer
Interventions
PROCEDURE

Partial mastectomy plus additional Shave Margin

"For the shave group, additional superior, inferior, medial and lateral margins will be removed, oriented, and sent for pathologic evaluation at the local site. Resection of additional anterior and posterior margins will be left to surgeon discretion, as this will depend on if skin or fascia was taken. All surgeons participating in the study will be educated on the expectation of what is considered a shave margin. A shave margin is defined as an additional segment of breast tissue taken from each of the superior, inferior, medial, and lateral aspects of the cavity, such that the entire circumference of the cavity is re-excised following this procedure. Orientation of each shaved margin will be done to mark the true margin."

PROCEDURE

Partial mastectomy

Surgeons will be instructed to close after partial mastectomy with no further excision.

Trial Locations (9)

19107

Thomas Jefferson University, Philadelphia

27157

Wake Forest School of Medicine, Winston-Salem

33805

Watson Clinic Cancer and Research Center, Lakeland

44307

Cleveland Clinic Akron General, Akron

48085

William Beaumont Hospital, Troy

78539

Doctors Hospital at Renaissance, Edinburg

92354

Loma Linda University Cancer Center, Loma Linda

27599-7213

UNC Chapel Hill, Chapel Hill

02905

Women & Infants Hospital, Providence

All Listed Sponsors
lead

Yale University

OTHER

NCT02772731 - Shave Margins vs. Standard Partial Mastectomy in Breast Cancer Patients | Biotech Hunter | Biotech Hunter