400
Participants
Start Date
July 31, 2016
Primary Completion Date
June 30, 2018
Study Completion Date
November 30, 2024
Partial mastectomy plus additional Shave Margin
"For the shave group, additional superior, inferior, medial and lateral margins will be removed, oriented, and sent for pathologic evaluation at the local site. Resection of additional anterior and posterior margins will be left to surgeon discretion, as this will depend on if skin or fascia was taken. All surgeons participating in the study will be educated on the expectation of what is considered a shave margin. A shave margin is defined as an additional segment of breast tissue taken from each of the superior, inferior, medial, and lateral aspects of the cavity, such that the entire circumference of the cavity is re-excised following this procedure. Orientation of each shaved margin will be done to mark the true margin."
Partial mastectomy
Surgeons will be instructed to close after partial mastectomy with no further excision.
Thomas Jefferson University, Philadelphia
Wake Forest School of Medicine, Winston-Salem
Watson Clinic Cancer and Research Center, Lakeland
Cleveland Clinic Akron General, Akron
William Beaumont Hospital, Troy
Doctors Hospital at Renaissance, Edinburg
Loma Linda University Cancer Center, Loma Linda
UNC Chapel Hill, Chapel Hill
Women & Infants Hospital, Providence
Yale University
OTHER