7
Participants
Start Date
May 31, 2016
Primary Completion Date
August 31, 2020
Study Completion Date
August 31, 2020
cyclophosphamide
60mg/kg by vein on day -6
Fludarabine
25mg/m2 iv daily on day -5 to -1
NK cell infusion
"* First allogeneic haploidentical NK cell iv. infusion: 5x10e7/kg, NK CD3-CD56+ immunophenotype, 24-48h after chemotherapy~* Second allogeneic haploidentical NK cell iv. infusion: up to 5x10e8/kg, NK CD3-CD56+immunophenotype, 7 days after the first infusion."
IL-2
1x10\^6 UI/m2 three times a week for two weeks from first NK infusion (day 0)
Hospital Universitario 12 de Octubre, Madrid
Hospital Universitario La Paz, Madrid
Hospital Materno-Infantil de Málaga, Málaga
Hospital de la Arrixaca, Murcia
Hospital Universitario de Cruces, Barakaldo
Hospital Materno Infantil de Badajoz, Badajoz
Hospital Infantil Universitario Niño Jesús, Madrid, Spain
OTHER
Fundación Mutua Madrileña
OTHER
Instituto de Investigación Hospital Universitario La Paz
OTHER