Work of Breathing Assessment During Weaning From Mechanical Ventilation

NACompletedINTERVENTIONAL
Enrollment

20

Participants

Timeline

Start Date

June 7, 2016

Primary Completion Date

June 30, 2017

Study Completion Date

June 30, 2017

Conditions
Mechanical Ventilation
Interventions
DEVICE

Measurement of work of breathing using indirect calorimeter

"1. Preparation:~ 1. Patient baseline characteristics will be collected.~ 2. Connection of the Indirect Calorimeter to the respiratory circuit.~ 3. Nasogastric tube installation: a specific modified Neurally Adjusted Ventilatory Assist (NAVA) catheter equipped with both microelectrodes for Electrical Activity of the diaphragme (EAdi) monitoring and an esophageal balloon (for esophageal pressure (PES) monitoring) will be installed.~2. Simultaneous recordings of: Oxygen Consumption (VO2) and Energy Expenditure (EE); Esophageal Pressure (PES), Airway Pressure (PAW), respiratory volume and flow; EAdi during (i) Conventional mechanical ventilation (ii) Spontaneous Breathing Trial in Continuous Positive Airway Pressure and (iii) Second period of Conventional mechanical ventilation with the same ventilator parameters set in STEP 1.~3. End of the physiological recordings. Collection of Pediatric Intensive Care Unit (PICU) outcome of patients."

Trial Locations (1)

H3T 1C5

St. Justine's Hospital, Montreal

All Listed Sponsors
lead

St. Justine's Hospital

OTHER

NCT02762292 - Work of Breathing Assessment During Weaning From Mechanical Ventilation | Biotech Hunter | Biotech Hunter