Myocardial Protection With Phosphocreatine in High-RIsk Cardiac SurgEry Patients

after anaesthesia induction 2 g of Phosphocreatine (PCr) prepared in 50 mL of glucose 5% during 30 min intravenous (IV)

after anaesthesia induction 50 mL of glucose 5% IV delivered by an identical infusion pump during 30 minutes

together with cardioplegia 2.5 g of PCr prepared in 50 mL of glucose 5% and added to every 1 L of cardioplegic solution (Custodiol, Dr. F. KOHLER CHEMIE, GmbH, Germany; concentration = 10 mmol/L)

together with cardioplegia 50 mL of glucose 5% is added in every 1 L of cardioplegic solution (Custodiol, Dr. F. KOHLER CHEMIE, GmbH, Germany)

immediately after heart recovery (spontaneous or paced myocardium contraction) after aorta declamping 2 g of PCr prepared in 50 mL of glucose 5% during 30 min IV

immediately after heart recovery (spontaneous or paced myocardium contraction) after aorta declamping 50 mL of glucose 5% IV delivered by an identical infusion pump during 30 minutes

immediately after ICU admission 4 g of PCr in 100 mL of glucose 5% during 60 min IV

immediately after ICU admission 100 mL of glucose 5% IV delivered by an identical infusion pump during 60 minutes