379
Participants
Start Date
October 13, 2016
Primary Completion Date
June 30, 2020
Study Completion Date
June 30, 2020
MRI
Recently-developed placenta-specific magnetic resonance imaging (MRI) tools will be used to quantify maternal perfusion and oxygen transfer throughout pregnancy in 3 groups of human subjects: 1) non-smokers, 2) smokers, 3) individuals at high risk for adverse outcome. The objective of this work is to develop a new non-invasive clinical tool for early identification of placental dysfunction.
MRI - IUGR
Recently-developed placenta-specific magnetic resonance imaging (MRI) tools will be used to quantify maternal perfusion and oxygen transfer throughout pregnancy. The objective of this ancillary arm is to further test the sensitivity of placental magnetic resonance imaging to detect abnormal perfusion and oxygenation in confirmed cases of IUGR between gestational ages 28 to 36 weeks.
University of Utah, Salt Lake City
Oregon Health and Science University, Portland
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Oregon Health and Science University
OTHER