STIM'ZO : Examining tDCS as an add-on Treatment for Persistent Symptoms in Schizophrenia

NACompletedINTERVENTIONAL
Enrollment

141

Participants

Timeline

Start Date

May 30, 2016

Primary Completion Date

May 31, 2022

Study Completion Date

October 19, 2022

Conditions
Mental DisordersSchizophrenia
Interventions
DEVICE

Neuroconn or Neuroelectric tDCS stimulator

Stimulation parameters were chosen in conformity with those for the treatment of schizophrenic symptoms (Brunelin et al, 2012), adapted according to the latest data from the literature and the tDCS operating stimulator. The experimental tDCS group will receive the ACTIVE stimulation with the following parameters: oscillatory Direct Current with high frequency random noise stimulation (hf-tRNS - 100 to 500 Hz), Intensity = 2 mA, offset = + 1 mA, seance duration = 20 minutes ramp up/ramp down 30 seconds. Total number of sessions = 10 (sessions twice daily for 5 days separated by at least 2 hours for 5 consecutive weekdays).

DEVICE

Sham tDCS

The control group will receive the SHAM stimulation (placebo) following the same regimen (i.e., twice daily sessions separated by at least 2 hours for 5 consecutive weekdays). Sham stimulation consists of a 20 minutes session including 40 seconds of active stimulation (same parameters as in the ACTIVE arm) at the beginning of the sessions, whatever the stimulator

Trial Locations (10)

14033

Centre Esquirol - CHU de Caen - Service de Psychiatrie Adulte,, Caen

34295

Hôpital de la Colombière - CHU Montpellier - Service de Psychiatrie Adulte, Montpellier

37044

CHRU de Tours - Clinique Psychiatrique Universitaire, Tours

42055

CHU de St-Etienne - Service d'Urgences Psychiatriques, Saint-Etienne

59037

Hôpital Fontan - CHRU de Lille - Pôle de Psychiatrie, Lille

63000

CHU de Clermont-Ferrand - Pôle de Psychiatrie B, Clermont-Ferrand

69437

Hôpital Edouard Herriot - Service d'Urgences Psychiatriques, Lyon

69678

Centre Hospitalier Le Vinatier - Service de Psychiatrie Adulte, Bron

75014

Centre Hospitalier Saint-Anne - Service de Psychiatrie Adultes, Paris

98000

Centre Hospitalier Princesse Grace - Service de Psychiatrie, Monaco

All Listed Sponsors
lead

Hospices Civils de Lyon

OTHER

NCT02744989 - STIM'ZO : Examining tDCS as an add-on Treatment for Persistent Symptoms in Schizophrenia | Biotech Hunter | Biotech Hunter