VentFirst: A Multicenter RCT of Assisted Ventilation During Delayed Cord Clamping for Extremely Preterm Infants

NAActive, not recruitingINTERVENTIONAL
Enrollment

570

Participants

Timeline

Start Date

June 30, 2016

Primary Completion Date

March 31, 2023

Study Completion Date

December 31, 2023

Conditions
Intraventricular Hemorrhage
Interventions
PROCEDURE

Standard 30-60 Seconds Cord Clamping

The infant is stimulated to breathe after birth. If the infant is not breathing well, the cord is clamped at 30 seconds. If the baby is breathing well, the cord is clamped at 60 seconds. Ventilatory assistance is given after cord clamping.

PROCEDURE

VentFirst 120 Seconds Cord Clamping

The infant is stimulated to breathe after birth. If the infant is not breathing well, PPV by face mask is given starting at 30 seconds. If the baby is breathing well, CPAP is given starting at 30 seconds. The cord is clamped at 120 seconds.

Trial Locations (12)

10032

Columbia University Medical Center, New York

35233

University of Alabama at Birmingham, Birmingham

46202

University of Indiana, Indianapolis

95817

University of California, Davis, Sacramento

80045-2571

University of Colorado, Denver

02115-6110

Brigham & Women's Hospital, Boston

55905-0001

Mayo Clinic, Rochester

63103-2006

St. Louis University, St Louis

37239-0000

Oregon Health & Science University, Portland

22904-4195

University of Virginia, Charlottesville

T2N 1N4

University of Calgary, Calgary

T5H 3V9

University of Alberta, Edmonton, Edmonton

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Brigham and Women's Hospital

OTHER

collaborator

Mayo Clinic

OTHER

collaborator

St. Louis University

OTHER

collaborator

University of Colorado, Denver

OTHER

collaborator

Oregon Health and Science University

OTHER

collaborator

University of Calgary

OTHER

collaborator

Columbia University

OTHER

collaborator

Indiana University

OTHER

collaborator

University of California, Davis

OTHER

collaborator

University of Alberta

OTHER

collaborator

University of Alabama at Birmingham

OTHER

lead

University of Virginia

OTHER

NCT02742454 - VentFirst: A Multicenter RCT of Assisted Ventilation During Delayed Cord Clamping for Extremely Preterm Infants | Biotech Hunter | Biotech Hunter