Role of Aromatase Inhibitor to Enhance Ovulation in Poor Responder During Induction With Short Antagonist Protocol in Cases of ICSI

PHASE4CompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

August 12, 2016

Primary Completion Date

August 24, 2017

Study Completion Date

September 3, 2017

Conditions
Infertility Indicated for ICSI
Interventions
DRUG

induction with aromataze inhibitor

letrozole 2.5mg once daily start in the first day of menses for 5days

DRUG

HMG

HMG 300 IU injection once daily start at first day of menses with follow up by trans vaginal ultrasound (TVUS ) till at least three follicles reach 14 mm in diameter

DRUG

GnRh a

antagonist given 0.1 ml injection once daily with continous follow up when at least three follicles reach 17mm in diameter HCG 10.000 IU injection and ovum pick up 24-36hours after injection

DRUG

HCG

10.000 IU HCG injection when at least three follicles reach 17mm in diameter

Trial Locations (1)

61519

Minia University, Minya

All Listed Sponsors
lead

Minia University

OTHER

NCT02741154 - Role of Aromatase Inhibitor to Enhance Ovulation in Poor Responder During Induction With Short Antagonist Protocol in Cases of ICSI | Biotech Hunter | Biotech Hunter