Naltrexone and Bupropion Combination on Obese,Smoking Patients With Schizophrenia

PHASE4CompletedINTERVENTIONAL
Enrollment

22

Participants

Timeline

Start Date

May 31, 2016

Primary Completion Date

July 31, 2018

Study Completion Date

July 31, 2018

Conditions
ObeseCigarette-smokingSchizophrenia
Interventions
DRUG

Naltrexone

3 tablets(15mg) once per day in the first two weeks,then Naltrexone 5 tablets(25mg) once per day during the rest of the study.

DRUG

Placebo Naltrexone

Placebo Naltrexone created and masked by the pharmacy to be used as a control.

DRUG

Bupropion

1 capsule(150mg) once per day in the first two weeks,then 2 capsules(300mg) once per day during the rest of the study.

DRUG

Placebo Bupropion

Placebo Bupropion created and masked by the pharmacy to be used as a control.

All Listed Sponsors
collaborator

University of Massachusetts, Worcester

OTHER

lead

Shanghai Mental Health Center

OTHER

NCT02736474 - Naltrexone and Bupropion Combination on Obese,Smoking Patients With Schizophrenia | Biotech Hunter | Biotech Hunter