Genetic Study of Immunodeficiency: Search for New Genetic Causes for Primary Immunodeficiencies

RecruitingOBSERVATIONAL
Enrollment

500

Participants

Timeline

Start Date

February 29, 2016

Primary Completion Date

July 31, 2027

Study Completion Date

December 31, 2027

Conditions
Immunologic Deficiency Syndromes
Interventions
PROCEDURE

blood sampling and skin biopsy

Nucleated blood cells and/or fibroblasts from skin biopsy will be used for genetic testing and functional assays. Blood serum will be used for antibody and cytokine measurement.

PROCEDURE

blood sampling or mouth swap

specimen will be used for genetic testing, results compared to patients

PROCEDURE

blood sampling

Nucleated blood cells and/or fibroblasts from skin biopsy will be used for genetic testing and functional assays. Blood serum will be used for antibody and cytokine measurement.

Trial Locations (2)

4031

RECRUITING

University of Basel Children's Hospital, Basel

8032

RECRUITING

Division of Immunology, Zurich

All Listed Sponsors
collaborator

University Children's Hospital Basel

OTHER

collaborator

University Hospital, Geneva

OTHER

lead

University Children's Hospital, Zurich

OTHER