Dexmedetomidine Sedation and Cardiopulmonary Bypass

PHASE2CompletedINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

April 30, 2016

Primary Completion Date

September 30, 2016

Study Completion Date

September 30, 2016

Conditions
Coronary Artery Bypass Grafting
Interventions
DRUG

Dexmedetomidine

Anesthesia will be maintained with continuous infusion of dexmedetomidine 0.5-0.7 µg/kg/h in addition to sevoflurane supplementation as required, to maintain arterial blood pressure and heart rate within 20% of preoperative values. Muscle relaxation will be maintained with continuous rocuronium infusion 0.6 mg/kg/h.

DRUG

propofol

Anesthesia will be maintained with continuous infusion of propofol 50-100 µg/kg/min in addition to sevoflurane supplementation as required, to maintain arterial blood pressure and heart rate within 20% of preoperative values. Muscle relaxation will be maintained with continuous rocuronium infusion 0.6 mg/kg/h.

Trial Locations (1)

Unknown

Faculty of Medicine, Asyut

All Listed Sponsors
lead

Assiut University

OTHER

NCT02727621 - Dexmedetomidine Sedation and Cardiopulmonary Bypass | Biotech Hunter | Biotech Hunter