40
Participants
Start Date
June 30, 2015
Primary Completion Date
November 30, 2016
Study Completion Date
March 31, 2017
Doxycycline
Application of 1 mg of doxyxycline microspheres at 4 sites (two means and two deep periodontal pockets) after mechanical debridement.
Mechanical debridement
Mechanical debridement (full mouth) of 45 minutes associated with the application of 1 mg of microspheres placebo in selected periodontal pockets.
Placebo
The application of 1 mg of microspheres placebo
Piracicaba Dental School, State University of Campinas, Piracicaba
Pontificia Universidade Catolica de Sao Paulo
OTHER
University of Campinas, Brazil
OTHER