Phase II Study Assessing the Efficacy and Safety of Lenvatinib for Anaplastic Thyroid Cancer

PHASE2CompletedINTERVENTIONAL
Enrollment

39

Participants

Timeline

Start Date

April 4, 2016

Primary Completion Date

February 25, 2020

Study Completion Date

March 20, 2020

Conditions
Anaplastic Thyroid Cancer
Interventions
DRUG

Lenvatinib

"All patients will receive lenvatinib 24 mg orally once daily at almost the same time. The treatment will be started within 1 week after enrollment. 1 cycle consists of 4 weeks.~The administration will be continued until patients meet withdrawal criteria. If any toxicity manifested that cannot be ruled out causal association with the study drug, drug withdrawal or dosage reduction will be conducted in accordance with drug withdrawal/dosage reduction criteria."

Trial Locations (23)

466-8560

Nagoya University Hospital, Nagoya

470-1192

Fujita Health University Hospital, Toyoake

272-0827

IUHW Ichikawa Hospital, Ichikawa

277-8577

National Cancer Center Hospital East, Kashiwa

286-8523

Japanese Red Cross Narita Hospital, Narita

650-0011

Kuma Hospital, Kobe

650-0017

Kobe Univbersity Hospital, Kobe

305-8576

University of Tsukuba Hospital, Tsukuba

020-8505

Iwate Medical University Hospital, Morioka

252-0375

Kitasato University Hospital, Sagamihara

224-8503

Showa University Northern Yokohama Hospital, Yokohama

241-8515

Kanagawa Cancer Center, Yokohama

981-1293

Miyaghi Cancer Center, Natori-shi

980-8574

Tohoku University Hospital, Sendai

390-8621

Shinsyu University School of Medicine Department of Surgery, Matsumoto

630-0293

Nara Hospital Kinki University Faculty of Medicine, Ikoma

634-8522

Nara Medical University, Kashihara

543-0035

Osaka Police Hospital, Osaka

545-8585

Osaka City University Graduate School of Medicine and Faculty of Medicine, Osaka

113-8603

Nippon Medical School Hospital, Bunkyo-ku

135-8550

The Cancer Institute Hospital of JFCR, Koto-ku

150-8308

Ito Hospital, Shibuya-ku

160-0023

Tokyo Medical University Hospital, Shinjuku-ku

All Listed Sponsors
lead

Translational Research Center for Medical Innovation, Kobe, Hyogo, Japan

OTHER

NCT02726503 - Phase II Study Assessing the Efficacy and Safety of Lenvatinib for Anaplastic Thyroid Cancer | Biotech Hunter | Biotech Hunter