75
Participants
Start Date
August 1, 2016
Primary Completion Date
May 31, 2019
Study Completion Date
June 1, 2019
of Lactobacillus reuteri (L. reuteri; DSM 17938)
Commercially available L. reuteri (deposited in the Deutsche Sammlung von Mikroorganismen und Zellkulturen (DSMZ) and referenced as DSM 17938; Gerber Soothe Colic Drops, 100 million CFU/5 drops; formerly known as L. reuteri ATCC 55730) will be used in the proposed study. L. reuteri (phylum Firmicutes) is a gram-positive anaerobic commensal bacteria found in the gut microbiome of humans. Independent testing of the viability of the commercial product will be conducted in our laboratories by diluting drops, plating on agar in triplicate, and anaerobic culturing at 37 oC. The commercial strain (DSM 17938) has been used to improve intestinal functions in infants and reduce symptoms of infantile colic.
Sunflower and medium chain triglyceride oils
Placebo
Rocky Mountain Regional VA Medical Center, Aurora, CO, Aurora
VA Office of Research and Development
FED