Effect of Terlipressin Infusion on Systemic and Hepatic Hemodynamics During Hepatobiliary Surgery

PHASE2CompletedINTERVENTIONAL
Enrollment

50

Participants

Timeline

Start Date

April 30, 2016

Primary Completion Date

July 31, 2017

Study Completion Date

July 31, 2017

Conditions
Hemodynamics, Liver, Terlipressin
Interventions
DRUG

terlipressin

Terlipressin will be started at the beginning of surgery as an initial bolus dose of 1 mg over 30 mints(1 mg/50 ml normal saline at a rate of 100 ml/h) followed by a continuous infusion of 2 μg/kg/h(1 mg/50 ml at a rate equal to wt/10 ml per hour) and weaned in the postoperative period over 4 hours.

DRUG

normal saline

Patients receive 50 ml normal saline at a rate of 100 ml/h followed by a continuous infusion of 50 ml at a rate equal to wt/10 ml per hour and weaned in the postoperative period over 4 hours.

Trial Locations (1)

11111

Assiut University hospital, Asyut

All Listed Sponsors
lead

Assiut University

OTHER

NCT02718599 - Effect of Terlipressin Infusion on Systemic and Hepatic Hemodynamics During Hepatobiliary Surgery | Biotech Hunter | Biotech Hunter