High-Volume Plasma Exchange Versus Standard Medical Treatment in Patients With Acute Liver Failure

NACompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

December 30, 2016

Primary Completion Date

October 8, 2018

Study Completion Date

October 18, 2018

Conditions
Acute Liver Failure
Interventions
BIOLOGICAL

Plasma Exchange

OTHER

Management of cerebral edema/intracranial hypertension:

OTHER

Transfer to Intensive Care Unit

DRUG

Prophylactic Antibiotics

OTHER

Intubation of trachea

OTHER

Administration of mannitol or 3% saline for severe elevation of Intra Cranial Pressure

OTHER

Volume Replacement

OTHER

Pressor Support

DRUG

N-acetyl-L-cysteine

OTHER

Correction of metabolic parameters

DIETARY_SUPPLEMENT

Correction of nutrition

Trial Locations (1)

110070

Institute of liver and Biliary Sciences, New Delhi

All Listed Sponsors
lead

Institute of Liver and Biliary Sciences, India

OTHER

NCT02718079 - High-Volume Plasma Exchange Versus Standard Medical Treatment in Patients With Acute Liver Failure | Biotech Hunter | Biotech Hunter