A Dose Frequency Optimization,Trial of Nivolumab 240 mg Every 2 Weeks vs Nivolumab 480 mg Every 4 Weeks in Subjects With Advanced or Metastatic Non-small Cell Lung Cancer Who Received Up to 12 Months of Nivolumab at 3 mg/kg or 240 mg Every 2 Weeks

PHASE3CompletedINTERVENTIONAL
Enrollment

363

Participants

Timeline

Start Date

May 24, 2016

Primary Completion Date

July 15, 2019

Study Completion Date

January 18, 2022

Conditions
Lung Cancer
Interventions
BIOLOGICAL

Nivolumab

Trial Locations (129)

1090

Local Institution, Vienna

2065

Local Institution - 0052, St Leonards

2145

Local Institution - 0117, Westmead

2298

Local Institution - 0118, Waratah

3084

Local Institution - 0053, Heidelberg

4102

Local Institution - 0093, Woolloongabba

5037

Local Institution - 0055, Kurralta Park

5042

Local Institution - 0054, Bedford Park

5112

Local Institution - 0056, Elizabeth Vale

6150

Local Institution - 0058, Murdoch

7000

Local Institution - 0057, Hobart

12206

Local Institution - 0035, Albany

13353

Local Institution - 0073, Berlin

13790

Local Institution - 0013, Johnson City

15224

Local Institution - 0005, Pittsburgh

20251

Local Institution - 0061, Hamburg

20817

Local Institution - 0042, Bethesda

20900

Local Institution - 0085, Monza

22042

Innova Schar Cancer Institute, Falls Church

22601

Shenandoah Oncology, Winchester

24105

Local Institution - 0106, Kiel

28374

Local Institution - 0127, Pinehurst

29414

Local Institution - 0020, Charleston

30029

Local Institution - 0078, Nîmes

30060

Local Institution - 0121, Marietta

30120

Local Institution - 0104, El Palmar

30607

Local Institution - 0008, Athens

30625

Local Institution - 0113, Hanover

31904

Local Institution - 0142, Columbus

32504

Local Institution - 0001, Pensacola

33021

Local Institution - 0089, Hollywood

33705

Local Institution - 0039, St. Petersburg

33901

Local Institution - 0038, Fort Myers

34125

Local Institution - 0064, Kassel

34471

Local Institution - 0026, Ocala

35016

Local Institution - 0068, Las Palmas de Gran Canaria

35205

Local Institution - 0004, Birmingham

35753

Local Institution - 0062, Greifenstein

37044

Local Institution - 0079, Tours

37203

Local Institution - 0036, Nashville

38138

Jones Clinic PC, Germantown

38801

Local Institution - 0116, Tupelo

39291

Local Institution, Lostau

41013

Local Institution - 0070, Seville

42003

Local Institution - 0112, Paducah

44109

MetroHealth Cancer Care Center, Cleveland

44646

Local Institution - 0129, Massillon

44708

Hematology And Oncology Associates, Canton

45242

Local Institution - 0037, Cincinnati

Local Institution - 0132, Cincinnati

46237

Innova Schar Cancer Institute, Indianapolis

46485

Local Institution - 0099, Fort Wayne

46804

Local Institution - 0050, Fort Wayne

47447

Local Institution - 0066, Moers

48075

Local Institution - 0136, Southfield

49000

Local Institution - 0081, Angers

Local Institution - 0105, Angers

54519

Local Institution - 0097, Vandœuvre-lès-Nancy

55100

Local Institution - 0086, Localita San Filippo Lucca

55404

Local Institution - 0120, Minneapolis

57105

Local Institution - 0124, Sioux Falls

60426

Ingalls Health System, Harvey

60714

Local Institution - 0098, Niles

61615

Local Institution - 0100, Peoria

63003

Local Institution - 0076, Clermont-Ferrand

64109

Local Institution - 0080, Bayonne

65806

Mercy Medical Research Institute, Springfield

67214

Local Institution - 0123, Wichita

68100

Local Institution - 0072, Mulhouse

68130

Local Institution - 0014, Omaha

69655

Local Institution - 0096, Villefranche-sur-Saône

70121

Local Institution - 0137, New Orleans

70809

Mary Bird Perkins Cancer Center, Baton Rouge

72000

Local Institution - 0077, Le Mans

75005

Local Institution - 0095, Paris

75014

Local Institution - 0083, Paris

75028

Local Institution - 0025, Flower Mound

75090

Texas Oncology, P.A., Sherman

75093

Texas Oncology, P.A., Plano

75230

Local Institution - 0011, Dallas

75231

Local Institution - 0022, Dallas

75601

Texas Oncology, P.A., Longview

76210

Texas Oncology, P.A., Denton

76310

Local Institution - 0034, Wichita Falls

77024

Texas Oncology, P.A., Houston

77479

Texas Oncology, P.A., Sugar Land

78212

Texas Oncology, P.A., San Antonio

79106

Texas Oncology - Amarillo, Amarillo

Local Institution, Freiburg im Breisgau

79701

Local Institution - 0119, Midland

79902

Texas Oncology, P.A., El Paso

80131

Local Institution - 0088, Napoli

80528

Local Institution - 0122, Fort Collins

82131

Local Institution - 0102, Gauting

85016

Local Institution - 0030, Phoenix

Local Institution - 0041, Phoenix

90095

Local Institution - 0046, Los Angeles

90227

Torrance Health Association, Redondo Beach

90419

Local Institution - 0067, Nuremberg

90706

Southern California Permanente Medical Group, Bellflower

92123

Sharp Memorial Hospital, San Diego

92835

St Jude Hospital Yorba Linda, Fullerton

92868

Local Institution - 0126, Orange

93015

Local Institution - 0010, Santa Barbara

93309

CBCC Global Research, Inc., Bakersfield

93454

Local Institution - 0044, Santa Maria

94589

Local Institution - 0130, Vallejo

95300

Local Institution, Pontoise

97504

Hematology Oncology Consultants, Pc, Medford

98684

Local Institution - 0031, Vancouver

98902

Yakima Valley Memorial Hospital/North Star Lodge, Yakima

99216

Cancer Care Northwest, Spokane Valley

99437

Local Institution, Bad Berka

80218-1210

Local Institution - 0017, Denver

61801-2594

Local Institution - 0143, Urbana

04412

Local Institution - 0109, Brewer

01107

Local Institution - 0125, Springfield

03756

Local Institution - 0141, Lebanon

79606-5208

Local Institution - 0023, Abilene

L3Y 2P9

Local Institution - 0059, Newmarket

H7M 3L9

Local Institution - 0146, Laval

H4J 1C5

Local Institution - 0145, Montreal

GIJ 1Z4

Local Institution, Québec

J7Z 5T3

Local Institution - 0060, Saint-Jérôme

92 151

Local Institution - 0075, Suresnes

01307

Local Institution - 0063, Dresden

04357

Local Institution - 0065, Leipzig

00128

Local Institution - 0087, Roma

08208

Local Institution - 0069, Barcelona

Sponsors
All Listed Sponsors
lead

Bristol-Myers Squibb

INDUSTRY

NCT02713867 - A Dose Frequency Optimization,Trial of Nivolumab 240 mg Every 2 Weeks vs Nivolumab 480 mg Every 4 Weeks in Subjects With Advanced or Metastatic Non-small Cell Lung Cancer Who Received Up to 12 Months of Nivolumab at 3 mg/kg or 240 mg Every 2 Weeks | Biotech Hunter | Biotech Hunter